There is no simple answer. The types of forage, soil quality, water, environment and other factors directly affect the number of animals you can maintain on a given acreage. Your local county extension agent, USDA Natural Resource Conservation Service, university's agricultural extension office, and local beef or dairy producers can all help you determine the carrying capacity of your acreage.
The number of beef animals allotted per acre in your area is a good initial estimate. You may find that you can run more bison per acre; however, it is best to start out with a safe number and adjust as you go. Remember, an adult animal eats more than a young animal and a lactating cow eats more than a non-lactating cow. (http://www.bisoncentral.com/about-bison/bison-per-acre-and-fencing)